Ovarian Cancer

Personalised treatments designed to fight cancer while minimising side effects.

What is Ovarian Cancer?

Ovarian cancer begins in the ovaries, the female reproductive organs that produce eggs and hormones such as estrogen and progesterone. Most ovarian cancers develop from the epithelial cells that cover the outer surface of the ovaries, while others may arise from germ cells (that form eggs) or stromal cells (that produce hormones). Because the ovaries are located deep within the pelvis, ovarian cancer often goes undetected until it has spread, making early detection and treatment crucial.

How common is ovarian cancer in the Philippines?

Ovarian cancer is one of the more common cancers affecting women in the Philippines and remains a significant cause of cancer-related deaths. 

According to the IARC Global Cancer Observatory (GLOBOCAN 2022): 

  • Among women, ovarian cancer is the 5th most common cancer, with an estimated 6,453 new cases in 2022 (about 6.1% of new cancer cases in females).
  • Across both sexes (all cancers), ovarian cancer ranked 9th in new cancer cases nationwide (6,453 cases; 3.4% of all new cancer cases in 2022).
  • Ovarian cancer caused an estimated 4,073 deaths in 2022 (ranked 7th among cancer deaths; 3.6% of all cancer deaths).  

These figures highlight why timely assessment and access to specialist care are important—especially when symptoms are persistent or worsening. 

What Are the Signs and Symptoms of Ovarian Cancer?

Early ovarian cancer often has no obvious symptoms. As the cancer grows, symptoms may include:

Because these symptoms can be vague and similar to other conditions, they are often overlooked. Women who experience persistent or worsening symptoms should consult a doctor promptly.

Screening for Ovarian Cancer

Unlike cervical cancer, there is no reliable population-wide screening test for ovarian cancer. Pelvic examinations, ultrasound scans, and blood tests such as CA-125 may help detect abnormalities but are not fully accurate for early detection. Women with strong family histories of ovarian or breast cancer, or those carrying BRCA1/BRCA2 mutations, may benefit from genetic testing and closer monitoring.

How is Ovarian Cancer Diagnosed?

Diagnosis typically involves:

  • Pelvic examination to detect abnormalities
  • Transvaginal ultrasound (TVUS) to examine the ovaries and surrounding tissues
  • Blood tests such as CA-125 levels, which may be elevated in ovarian cancer
  • Imaging tests (CT, MRI, PET scans) to determine cancer spread
  • Biopsy or surgery (laparoscopy/laparotomy) to confirm cancer and its type

What Are the Causes and Risk Factors of Ovarian Cancer?

The exact cause is not known, but several factors increase the risk:

Protective factors include childbirth, breastfeeding, and use of oral contraceptives, which may lower the risk.

What Are the Types of Ovarian Cancer?

Epithelial ovarian cancer

Most common type (about 90% of cases)

Rare, often occur in younger women

Arise from hormone-producing cells, usually diagnosed at an earlier stage

What Are The Stages of Ovarian Cancer?

Staging helps determine treatment options:
Stage I

Cancer confined to one or both ovaries

Cancer has spread to the pelvis (uterus, fallopian tubes)

Cancer has spread to the abdomen or lymph nodes

Cancer has spread to distant organs such as the liver or lungs

What are Ovarian Cancer Treatments?

Treatment depends on stage, type, and overall health:

Surgery

Removal of one or both ovaries, fallopian tubes, uterus, and affected tissues.

Targeted Therapy

PARP inhibitors (for patients with BRCA mutations) and angiogenesis inhibitors.

Hormonal Therapy

Occasionally used for stromal tumours.

Immunotherapy

Emerging options that may benefit certain patients.

Clinical Trials

Emerging options that may benefit certain patients.

At OncoCare Philippines, our specialists tailor treatments to each patient, balancing cancer control with quality of life.

Meet Our Doctors

At OncoCare Philippines, our multidisciplinary team includes oncologists specialising in ovarian and gynaecological cancers, gynaecologic surgeons skilled in complex and minimally invasive procedures, radiation oncologists, radiologists, and pathologists. Our oncology nurses, nutritionists, fertility counsellors, and psycho-oncology experts provide holistic support to help patients through every stage of their journey. Together, they design a personalised treatment plan for each patient.

Dr. Angelo Miguel M. Realina
Palliative Care Specialist | Interventional Pain Management Specialist
Dr. Arthur Jason S. Go
Medical Oncologist
Dr. Beverly Ann P. Pineda
Medical Oncologist 
Dr. Carlo Ruperto P. Aguilar
Radiation Oncologist
Dr. Carlos Joseph T. Panaligan Jr.
Consultant Anesthesiologist
Dr. Claudine Yvette S. Gulapa
Anesthesiologist
Dr. Gonzalo C. Banuelos, Jr.
Radiation Oncologist
Dr. Jason King D. Talao
Medical Oncologist 
Dr. Jerickson Abbie S. Flores
Radiation Oncologist
Dr. Joel R. Tayo
Medical Oncologist
Dr. Jose Enrique Y. Montoya
Medical Oncologist
Dr. Karl Jeremy B. Lo
Radiation Oncologist
Dra. Kristine Anne B. Monte
Internal Medicine Specialist
Dr. Marwin M. Manalo
Medical Oncologist
Dr. Misael C. Cruz
Radiation Oncologist
Dr. Noel S. Chua
Medical Oncologist
Dr. Paulo S. Tioleco
Medical Oncologist
Dra. Rosalina P. Tongol
Internal Medicine