Colorectal (Colon) Cancer

Personalised treatments designed to fight cancer while minimising side effects.

What is Colorectal (Colon) Cancer?

Colorectal cancer (CRC) develops in the colon or rectum, often beginning as small growths called polyps that can turn cancerous over time if not removed. Because the colon and rectum are part of the digestive tract, colorectal cancer is sometimes referred to as “colon cancer.”

In Philippines, colorectal cancer is the most common cancer among men and the second most common among women, according to the Philippines National Cancer Registry (MNCRR 2017–2021). Unfortunately, a significant proportion of patients are still diagnosed at Stage 3 or 4, when the disease is harder to treat effectively.

How common is colorectal cancer in the Philippines?

Colorectal cancer (cancer of the colon and rectum) is a major cancer burden in the Philippines. 

According to the IARC Global Cancer Observatory (GLOBOCAN 2022): 

  • Colorectal cancer is the 3rd most common cancer overall in the Philippines, with an estimated 20,736 new cases in 2022—about 11.0% of all new cancer cases. 
  • It is also a leading cause of cancer death, with an estimated 10,692 deaths in 2022 (ranked 4th among all cancers). 
  • The estimated age-standardized incidence rate (ASR) for colorectal cancer (both sexes) is 20.8 per 100,000, and the age-standardized mortality rate is 10.8 per 100,000.  

Because colorectal cancer can often be detected earlier through screening, improving access to appropriate screening tests—such as stool-based tests (e.g., FIT) followed by confirmatory procedures when needed—can help improve outcomes. 

What Are the Signs and Symptoms of Colorectal Cancer?

In its early stages, colorectal cancer may cause no noticeable symptoms. As the cancer grows, symptoms may include:

These symptoms may be caused by other conditions, but if they persist, medical evaluation is important.

Screening for Colorectal Cancer

Early detection through screening saves lives. In Philippines, guidelines recommend:

  • Faecal Immunochemical Test (FIT) – A stool test to detect hidden blood. Recommended yearly or biennially for adults aged 50 and above, or earlier if high risk
  • Colonoscopy – The gold standard for detecting and removing polyps before they turn cancerous. Typically advised every 10 years for average-risk individuals, sooner if family history or other risk factors are present
  • Flexible Sigmoidoscopy – May be used as an alternative in some cases

Individuals with a family history of colorectal cancer, inflammatory bowel disease, or genetic syndromes such as Lynch syndrome should begin screening earlier and repeat it more frequently.

How is Colorectal Cancer Diagnosed?

Diagnosis usually involves:

What Are the Causes and Risk Factors of Colorectal Cancer?

While the exact cause is not always known, several risk factors increase the likelihood of developing colorectal cancer:

  • Age 50 and above
  • Family history of colorectal cancer or polyps
  • Hereditary syndromes (e.g., Lynch syndrome)
  • Diet low in fibre and high in red or processed meats
  • Obesity and lack of physical activity
  • Smoking and heavy alcohol intake
  • Inflammatory bowel disease (ulcerative colitis, Crohn’s disease)

What Are the Types of Colorectal Cancer?

The most common types include:

What Are the Stages of Colorectal Cancer?

Staging describes how advanced the cancer is:

Stage 0 (in situ)

Cancer cells limited to the innermost lining

Cancer confined to the colon/rectum wall or slightly beyond, no lymph nodes

Cancer has spread to nearby lymph nodes

Cancer has spread (metastasised) to distant organs like the liver or lungs

The stage at diagnosis is critical in determining treatment and prognosis.

What Are Colorectal Cancer Treatments?

Treatment depends on the stage, overall health, and fertility wishes of the patient.

Polypectomy

(Removal of polyps) during colonoscopy

Surgery

(Laparoscopic or robotic) to remove the tumour and nearby lymph nodes

Surgery + adjuvant chemotherapy

(To reduce recurrence)

Chemoradiation

Often used for rectal cancers before surgery

Systemic chemotherapy

(E.g., FOLFOX, FOLFIRI)

Targeted Therapy

(Anti-EGFR or anti-VEGF agents, depending on tumour genetics)

Immunotherapy

PD-1 inhibitors) for MSI-H/dMMR cancers

Metastasis-directed treatment

(Surgery, ablation) in selected patients

Palliative treatments

To control symptoms and maintain quality of life

How common is colorectal cancer in the Philippines?

Colorectal cancer (cancer of the colon and rectum) is a major cancer burden in the Philippines. 

According to the IARC Global Cancer Observatory (GLOBOCAN 2022): 

  • Colorectal cancer is the 3rd most common cancer overall in the Philippines, with an estimated 20,736 new cases in 2022—about 11.0% of all new cancer cases.
  • It is also a leading cause of cancer death, with an estimated 10,692 deaths in 2022 (ranked 4th among all cancers).
  • The estimated age-standardized incidence rate (ASR) for colorectal cancer (both sexes) is 20.8 per 100,000, and the age-standardized mortality rate is 10.8 per 100,000.  

Because colorectal cancer can often be detected earlier through screening, improving access to appropriate screening tests—such as stool-based tests (e.g., FIT) followed by confirmatory procedures when needed—can help improve outcomes. 

Meet Our Doctors

In Philippines, our team includes colorectal oncologists, surgeons, radiation specialists, pathologists, nurses and allied health professionals. They work together to deliver personalised treatment and care for every patient.

Dr. Angelo Miguel M. Realina
Palliative Care Specialist | Interventional Pain Management Specialist
Dr. Arthur Jason S. Go
Medical Oncologist
Dr. Beverly Ann P. Pineda
Medical Oncologist 
Dr. Carlo Ruperto P. Aguilar
Radiation Oncologist
Dr. Carlos Joseph T. Panaligan Jr.
Consultant Anesthesiologist
Dr. Claudine Yvette S. Gulapa
Anesthesiologist
Dr. Gonzalo C. Banuelos, Jr.
Radiation Oncologist
Dr. Jason King D. Talao
Medical Oncologist 
Dr. Jerickson Abbie S. Flores
Radiation Oncologist
Dr. Joel R. Tayo
Medical Oncologist
Dr. Jose Enrique Y. Montoya
Medical Oncologist
Dr. Karl Jeremy B. Lo
Radiation Oncologist
Dra. Kristine Anne B. Monte
Internal Medicine Specialist
Dr. Marwin M. Manalo
Medical Oncologist
Dr. Misael C. Cruz
Radiation Oncologist
Dr. Noel S. Chua
Medical Oncologist
Dr. Paulo S. Tioleco
Medical Oncologist
Dra. Rosalina P. Tongol
Internal Medicine